3obz: Difference between revisions
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{{STRUCTURE_3obz| PDB=3obz | SCENE= }} | {{STRUCTURE_3obz| PDB=3obz | SCENE= }} | ||
===Crystal structure of human phytanoyl-COA dioxygenase phyhd1 2-oxoglutarate and iron complex=== | ===Crystal structure of human phytanoyl-COA dioxygenase phyhd1 2-oxoglutarate and iron complex=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/PHYD1_HUMAN PHYD1_HUMAN]] Isoform 1 has alpha-ketoglutarate-dependent dioxygenase activity. Does not show detectable activity towards fatty acid CoA thioesters. Is not expected to be active with phytanoyl CoA. Isoform 2 and isoform 3 probably lack enzyme activity.<ref>PMID:21530488</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3obz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OBZ OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: McDonough, M A.]] | [[Category: McDonough, M A.]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Oxygenase]] | [[Category: Oxygenase]] | ||
Revision as of 08:20, 2 May 2013
Crystal structure of human phytanoyl-COA dioxygenase phyhd1 2-oxoglutarate and iron complex
Function
[PHYD1_HUMAN] Isoform 1 has alpha-ketoglutarate-dependent dioxygenase activity. Does not show detectable activity towards fatty acid CoA thioesters. Is not expected to be active with phytanoyl CoA. Isoform 2 and isoform 3 probably lack enzyme activity.[1]
About this Structure
3obz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- ↑ Zhang Z, Kochan GT, Ng SS, Kavanagh KL, Oppermann U, Schofield CJ, McDonough MA. Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase. Biochem Biophys Res Commun. 2011 May 20;408(4):553-8. doi:, 10.1016/j.bbrc.2011.04.059. Epub 2011 Apr 21. PMID:21530488 doi:10.1016/j.bbrc.2011.04.059
