Calmodulin: Difference between revisions
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{{STRUCTURE_1prw| PDB=1prw | SIZE=300| SCENE= |right|CAPTION=Calmodulin, [[1prw]] }} | {{STRUCTURE_1prw| PDB=1prw | SIZE=300| SCENE= |right|CAPTION=Calmodulin, [[1prw]] }} | ||
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[[Calmodulin]] (CaM) – calcium modulated protein – regulates various protein targets. It is used by various proteins as calcium sensor and signal transducer by binding to their calcium binding domain (CBD). It undergoes conformational change upon binding Ca++ via its 4 EF hand motives and can undergo post-translational modification. | [[Calmodulin]] (CaM) – calcium modulated protein – regulates various protein targets. It is used by various proteins as calcium sensor and signal transducer by binding to their calcium binding domain (CBD). It undergoes conformational change upon binding Ca++ via its 4 EF hand motives and can undergo post-translational modification. | ||
The images at the left and at the right correspond to one representative calmodulin, ''i.e.'' crystal structure of bovine brain Ca++ calmodulin in a compact form ([[1prw]]). | |||
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<applet load='1cll' size='350' color='white' frame='true' align='right' caption='Calmodulin' scene='Calmodulin/Inicio/1' /> | <applet load='1cll' size='350' color='white' frame='true' align='right' caption='Calmodulin' scene='Calmodulin/Inicio/1' /> | ||
Revision as of 07:58, 2 September 2010
Under contstruction... Calmodulin (CaM) – calcium modulated protein – regulates various protein targets. It is used by various proteins as calcium sensor and signal transducer by binding to their calcium binding domain (CBD). It undergoes conformational change upon binding Ca++ via its 4 EF hand motives and can undergo post-translational modification. The images at the left and at the right correspond to one representative calmodulin, i.e. crystal structure of bovine brain Ca++ calmodulin in a compact form (1prw).
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Conformational change of Calmodulin
See Also
- Calmodulin at Wikipedia
- Molecule of the Month (08/2003) at RCSB PDB
- Template:Proteopedia page for Calmodulin crystal complex between calmodulin and alpha11-spectrin
Proteopedia Page Contributors and Editors (what is this?)
Alexander Berchansky, Karsten Theis, Enrico Ravera, Daniel Moyano-Marino, Jaime Prilusky, Michal Harel
