User:Helen Ginn

Undergraduate Student in Biochemistry at Oxford University.
Website: [[1]]

A link

/Workbench I am a link to my workbench

Pages to which I contribute

T-box proteins.

Testing scenes in TBX3

spinqualitylabelsall models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D load='1h6f' size='350' frame='false' scene=
1h6f, resolution 1.70Å (default scene)
Ligands:	MG
Structural annotation: Resources: CATH : 1H6Fa00, 1H6Fb00 InterPro : Ipr001699, Ipr008967 Pfam : PF00907 SCOP : d1h6fa_, d1h6fb_ UniProt : O15119
Functional annotation: Cellular component: nucleus Biological process: positive regulation of cell proliferation embryonic digit morphogenesis regulation of transcription from RNA polymerase II promoter cell aging negative regulation of myoblast differentiation multicellular organismal development anti-apoptosis follicle-stimulating hormone secretion luteinizing hormone secretion male genitalia development transcription negative regulation of transcription, DNA-dependent regulation of transcription, DNA-dependent skeletal development positive regulation of cell cycle determination of anterior/posterior axis, embryo forelimb morphogenesis female genitalia development embryonic arm morphogenesis organ morphogenesis mammary gland development mesoderm morphogenesis Molecular function: transcription repressor activity DNA binding general transcriptional repressor activity transcription factor activity sequence-specific DNA binding RNA polymerase II transcription factor activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

3₁₀ helix interacting with DNA with residues N277, F279, K281 and F283.

N277 only

F279 only

F281 only

F283 only

Now try zooming in to Chain A.

TBX3 3_10 helix interacting with DNA.

Proteopedia Page Contributors and Editors (what is this?)

Helen Ginn, Eran Hodis