3nw5: Difference between revisions

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{{Seed}}
[[Image:3nw5.png|left|200px]]
[[Image:3nw5.png|left|200px]]


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{{STRUCTURE_3nw5|  PDB=3nw5  |  SCENE=  }}  
{{STRUCTURE_3nw5|  PDB=3nw5  |  SCENE=  }}  


===Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11B)===
===Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11B)===


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{{ABSTRACT_PUBMED_20675137}}
{{ABSTRACT_PUBMED_20675137}}


==About this Structure==
==About this Structure==
3NW5 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NW5 OCA].  
[[3nw5]] is a 1 chain structure of [[Hormone]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NW5 OCA].  
 
==See Also==
*[[Hormone|Hormone]]


==Reference==
==Reference==
<ref group="xtra">PMID:20675137</ref><references group="xtra"/>
<ref group="xtra">PMID:020675137</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Kinase domain]]
[[Category: Kinase domain]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 13:35:45 2010''

Revision as of 01:39, 27 July 2012

File:3nw5.png

Template:STRUCTURE 3nw5

Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11B)

Template:ABSTRACT PUBMED 20675137

About this Structure

3nw5 is a 1 chain structure of Hormone with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sampognaro AJ, Wittman MD, Carboni JM, Chang C, Greer AF, Hurlburt WW, Sack JS, Vyas DM. Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5027-30. Epub 2010 Jul 15. PMID:20675137 doi:10.1016/j.bmcl.2010.07.045

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