3nvx: Difference between revisions
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{{STRUCTURE_3nvx| PDB=3nvx | SCENE= }} | {{STRUCTURE_3nvx| PDB=3nvx | SCENE= }} | ||
===Molecular mechanism of guidance cue recognition=== | ===Molecular mechanism of guidance cue recognition=== | ||
{{ABSTRACT_PUBMED_20727575}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/VA39_VACCC VA39_VACCC]] Acts as a semaphorin-like protein and binds to host plexin C1 receptor. May alter the movement of host plexin C1-expressing cells including dendritic cells, monocytes, or granulocytes in the proximity of infected cells. May also regulate host cell cytoskeleton of neighboring cells to improve viral infection (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
[[3nvx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NVX OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020727575</ref><references group="xtra"/><references/> | ||
[[Category: Vaccinia virus | [[Category: Vaccinia virus]] | ||
[[Category: Chen, X.]] | [[Category: Chen, X.]] | ||
[[Category: Focia, P.]] | [[Category: Focia, P.]] | ||
| Line 34: | Line 21: | ||
[[Category: Beta-propeller]] | [[Category: Beta-propeller]] | ||
[[Category: Viral protein]] | [[Category: Viral protein]] | ||
Revision as of 11:42, 24 April 2013
Molecular mechanism of guidance cue recognition
Template:ABSTRACT PUBMED 20727575
Function
[VA39_VACCC] Acts as a semaphorin-like protein and binds to host plexin C1 receptor. May alter the movement of host plexin C1-expressing cells including dendritic cells, monocytes, or granulocytes in the proximity of infected cells. May also regulate host cell cytoskeleton of neighboring cells to improve viral infection (By similarity).
About this Structure
3nvx is a 2 chain structure with sequence from Vaccinia virus. Full crystallographic information is available from OCA.
Reference
- Liu H, Juo ZS, Shim AH, Focia PJ, Chen X, Garcia KC, He X. Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1. Cell. 2010 Sep 3;142(5):749-61. Epub 2010 Aug 19. PMID:20727575 doi:10.1016/j.cell.2010.07.040
