Agrin

File:3i70.jpg

Crystal Structure of chicken Agrin, 3i70

Agrin (Agr) is involved in the embryogenesis of the neuromuscular junction. It is involved in the aggregation of acetylcholine receptors. Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, i.e. the crystal structure of chicken Agrin (3i70).

3D Structures of Agrin

3i70, 1pxu – cNtA – chicken
1pz7, 1pz8, 1pz9 – cAgr
1q56 – cAgr-G3+Ca – NMR
1jb3, 1jc7 – cAgr LMB

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Joel L. Sussman