3mn3: Difference between revisions
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{{STRUCTURE_3mn3| PDB=3mn3 | SCENE= }} | {{STRUCTURE_3mn3| PDB=3mn3 | SCENE= }} | ||
===An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1=== | ===An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1=== | ||
{{ABSTRACT_PUBMED_20823513}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SNF1_YEAST SNF1_YEAST]] Essential for release from glucose repression. It interacts and has functional relationship to the regulatory protein SNF4. Could phosphorylate CAT8. Phosphorylates histone H3 to form H3S10ph, which promotes H3K14ac formation, and which is required for transcriptional activation through TBP recruitment to the promoters.<ref>PMID:15719021</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3mn3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MN3 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020823513</ref><references group="xtra"/><references/> | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| Line 33: | Line 20: | ||
[[Category: Snf1]] | [[Category: Snf1]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 21:01, 17 April 2013
An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1
Template:ABSTRACT PUBMED 20823513
Function
[SNF1_YEAST] Essential for release from glucose repression. It interacts and has functional relationship to the regulatory protein SNF4. Could phosphorylate CAT8. Phosphorylates histone H3 to form H3S10ph, which promotes H3K14ac formation, and which is required for transcriptional activation through TBP recruitment to the promoters.[1]
About this Structure
3mn3 is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
- Rudolph MJ, Amodeo GA, Tong L. An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt, 9):999-1002. Epub 2010 Aug 21. PMID:20823513 doi:10.1107/S1744309110028265
