2qud: Difference between revisions
New page: left|200px<br /><applet load="2qud" size="350" color="white" frame="true" align="right" spinBox="true" caption="2qud, resolution 1.60Å" /> '''PP7 Coat Protein Dim... |
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==Overview== | ==Overview== | ||
The cocrystal structure of the PP7 bacteriophage coat protein in complex | The cocrystal structure of the PP7 bacteriophage coat protein in complex with its translational operator identifies a distinct mode of sequence-specific RNA recognition when compared to the well-characterized MS2 coat protein-RNA complex. The structure reveals the molecular basis of the PP7 coat protein's ability to selectively bind its cognate RNA, and it demonstrates that the conserved beta-sheet surface is a flexible architecture that can evolve to recognize diverse RNA hairpins. | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Enterobacteria phage p21]] | [[Category: Enterobacteria phage p21]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Chao, J | [[Category: Chao, J A.]] | ||
[[Category: GOL]] | [[Category: GOL]] | ||
[[Category: bacteriophage]] | [[Category: bacteriophage]] | ||
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[[Category: rna-protein complex]] | [[Category: rna-protein complex]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:42:21 2008'' | ||
Revision as of 16:42, 21 February 2008
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PP7 Coat Protein Dimer
Overview
The cocrystal structure of the PP7 bacteriophage coat protein in complex with its translational operator identifies a distinct mode of sequence-specific RNA recognition when compared to the well-characterized MS2 coat protein-RNA complex. The structure reveals the molecular basis of the PP7 coat protein's ability to selectively bind its cognate RNA, and it demonstrates that the conserved beta-sheet surface is a flexible architecture that can evolve to recognize diverse RNA hairpins.
About this Structure
2QUD is a Single protein structure of sequence from Enterobacteria phage p21 with GOL as ligand. Full crystallographic information is available from OCA.
Reference
Structural basis for the coevolution of a viral RNA-protein complex., Chao JA, Patskovsky Y, Almo SC, Singer RH, Nat Struct Mol Biol. 2008 Jan;15(1):103-5. Epub 2007 Dec 9. PMID:18066080
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