RNA Interference: Difference between revisions
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David Canner (talk | contribs) New page: 350px|right|thumb| Schematic of RNAi Interference in Mammalian Cells RNA Interference (RNAi) is a system in living cells that helps control the le... |
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[[Image:500px-ShRNA Lentivirus.png|350px|right|thumb| Schematic of RNAi Interference in Mammalian Cells]] | [[Image:500px-ShRNA Lentivirus.png|350px|right|thumb| Schematic of RNAi Interference in Mammalian Cells]] | ||
[[RNA Interference]] (RNAi) is a system in living cells that helps control the level of activity of genes. In RNAi, a long double stranded RNA is cleaved into shorter strands. One strand known as the guide strand is complimentary to the mRNA gene product of a gene of interest. This guide strand is incorporated into an RNA-induced silencing complex (RISC) and subsequently binds the mRNA of the gene of interest. After binding, the RNA/RISC complex subsequently silences the mRNA of interest via cleavage of the mRNA strand. | [[RNA Interference]] (RNAi) is a system in living cells that helps control the level of activity of genes. In RNAi, a long double stranded [[RNA]] is cleaved into shorter strands. One strand known as the guide strand is complimentary to the mRNA gene product of a gene of interest. This guide strand is incorporated into an RNA-induced silencing complex (RISC) and subsequently binds the mRNA of the gene of interest. After binding, the RNA/RISC complex subsequently silences the mRNA of interest via cleavage of the mRNA strand. | ||
Articles in Proteopedia concerning RNA Interference include: | Articles in Proteopedia concerning RNA Interference include: | ||
