B-RAF with PLX4032: Difference between revisions
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PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. | PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. | ||
<scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br> | <scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br> | ||
Revision as of 01:17, 29 September 2010
B-RAF with PLX4032
PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF.
PLX 4032
V600E mutation
DFG in
DFG out
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