Acetylcholine: Difference between revisions
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===Additional Resources=== | ===Additional Resources=== | ||
For additional information, see: [[Alzheimer's]] | For additional information, see: [[Alzheimer's Disease]] | ||
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Revision as of 09:43, 1 October 2010

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Acetylcholine at the Wikipedia
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Acetylcholinesterase (EC 3.1.1.7, e.g. from Torpedo californica, TcAChE) hydrolysizes the neurotransmitter acetylcholine (ACh), producing choline and an acetate group. ACh directly binds Ser200 (via its nucleophilic Oγ atom) within the catalytic triad (Ser200, His440, and Glu327) of (ACh/TcAChE structure 2ace). The residues Trp84 and Phe330 are also important in the ligand recognition.
Additional Resources
For additional information, see: Alzheimer's Disease
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Joel L. Sussman, Alexander Berchansky, Ralf Stephan, Harry Greenblatt, David Canner