T-box proteins: Difference between revisions
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=Gene loci and structure= | =Gene loci and structure= | ||
The loci of these genes are dispersed throughout the genomes of relevant oragnisms, though a few select cases of clustering exist. Tight linkages include Tbx8 and Tbx9 in ''C. elegans'', and in mice: Tbx2 and Tbx4 on chromosome 11; and | The loci of these genes are dispersed throughout the genomes of relevant oragnisms, though a few select cases of clustering exist. Tight linkages include Tbx8 and Tbx9 in ''C. elegans'', and in mice: Tbx2 and Tbx4 on chromosome 11; and [[TBX3]] and [[TBX5]] on chromosome 5. Similar linkages are present in humans. These genes include multiple exons, typically 8 (as in Tbx5). There are a few cases of alternative splicing, such as VegT in ''Xenopus'' and [[TBX1]] in humans. | ||
=Protein structure= | =Protein structure= | ||