T-box proteins: Difference between revisions

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=Gene loci and structure=
=Gene loci and structure=


The loci of these genes are dispersed throughout the genomes of relevant oragnisms, though a few select cases of clustering exist.  Tight linkages include Tbx8 and Tbx9 in ''C. elegans'', and in mice: Tbx2 and Tbx4 on chromosome 11; and Tbx3 and Tbx5 on chromosome 5.  Similar linkages are present in humans.  These genes include multiple exons, typically 8 (as in Tbx5).  There are a few cases of alternative splicing, such as VegT in ''Xenopus'' and [[TBX1]] in humans.
The loci of these genes are dispersed throughout the genomes of relevant oragnisms, though a few select cases of clustering exist.  Tight linkages include Tbx8 and Tbx9 in ''C. elegans'', and in mice: Tbx2 and Tbx4 on chromosome 11; and [[TBX3]] and [[TBX5]] on chromosome 5.  Similar linkages are present in humans.  These genes include multiple exons, typically 8 (as in Tbx5).  There are a few cases of alternative splicing, such as VegT in ''Xenopus'' and [[TBX1]] in humans.


=Protein structure=
=Protein structure=