3bue: Difference between revisions

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==Overview==

The gene product of an open reading frame Rv1657 from Mycobacterium, tuberculosis is a putative arginine repressor protein (ArgR), a, transcriptional factor that regulates the expression of, arginine-biosynthetic enzymes. Rv1657 was expressed and purified and a, C-terminal domain was crystallized using the hanging-drop vapour-diffusion, method. Diffraction data were collected and processed to a resolution of, 2.15 A. The crystals belong to space group P1 and the Matthews coefficient, suggests that the crystals contain six C-terminal domain molecules per, unit cell. Previous structural and biochemical studies on the arginine, repressor proteins from other organisms have likewise shown the presence, of six molecules per unit cell.

The gene product of an open reading frame Rv1657 from Mycobacterium tuberculosis is a putative arginine repressor protein (ArgR), a transcriptional factor that regulates the expression of arginine-biosynthetic enzymes. Rv1657 was expressed and purified and a C-terminal domain was crystallized using the hanging-drop vapour-diffusion method. Diffraction data were collected and processed to a resolution of 2.15 A. The crystals belong to space group P1 and the Matthews coefficient suggests that the crystals contain six C-terminal domain molecules per unit cell. Previous structural and biochemical studies on the arginine repressor proteins from other organisms have likewise shown the presence of six molecules per unit cell.

==About this Structure==

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[[Category: Mycobacterium tuberculosis h37rv]]

[[Category: Single protein]]

[[Category: Cherney, L.T.]]

[[Category: Cherney, L T.]]

[[Category: Cherney, M.M.]]

[[Category: Cherney, M M.]]

[[Category: Garen, C.R.]]

[[Category: Garen, C R.]]

[[Category: James, M.N.G.]]

[[Category: James, M N.G.]]

[[Category: Lu, G.J.]]

[[Category: Lu, G J.]]

[[Category: TBSGC, TB.Structural.Genomics.Consortium.]]

[[Category: TBSGC, TB Structural Genomics Consortium.]]

[[Category: amino-acid biosynthesis]]

[[Category: arginine biosynthesis]]

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[[Category: transcription regulation]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:07:38 2008''

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@@ Line 4: / Line 4: @@
 ==Overview==
-The gene product of an open reading frame Rv1657 from Mycobacterium, tuberculosis is a putative arginine repressor protein (ArgR), a, transcriptional factor that regulates the expression of, arginine-biosynthetic enzymes. Rv1657 was expressed and purified and a, C-terminal domain was crystallized using the hanging-drop vapour-diffusion, method. Diffraction data were collected and processed to a resolution of, 2.15 A. The crystals belong to space group P1 and the Matthews coefficient, suggests that the crystals contain six C-terminal domain molecules per, unit cell. Previous structural and biochemical studies on the arginine, repressor proteins from other organisms have likewise shown the presence, of six molecules per unit cell.
+The gene product of an open reading frame Rv1657 from Mycobacterium tuberculosis is a putative arginine repressor protein (ArgR), a transcriptional factor that regulates the expression of arginine-biosynthetic enzymes. Rv1657 was expressed and purified and a C-terminal domain was crystallized using the hanging-drop vapour-diffusion method. Diffraction data were collected and processed to a resolution of 2.15 A. The crystals belong to space group P1 and the Matthews coefficient suggests that the crystals contain six C-terminal domain molecules per unit cell. Previous structural and biochemical studies on the arginine repressor proteins from other organisms have likewise shown the presence of six molecules per unit cell.
 ==About this Structure==
@@ Line 13: / Line 13: @@
 [[Category: Mycobacterium tuberculosis h37rv]]
 [[Category: Single protein]]
-[[Category: Cherney, L.T.]]
+[[Category: Cherney, L T.]]
-[[Category: Cherney, M.M.]]
+[[Category: Cherney, M M.]]
-[[Category: Garen, C.R.]]
+[[Category: Garen, C R.]]
-[[Category: James, M.N.G.]]
+[[Category: James, M N.G.]]
-[[Category: Lu, G.J.]]
+[[Category: Lu, G J.]]
-[[Category: TBSGC, TB.Structural.Genomics.Consortium.]]
+[[Category: TBSGC, TB Structural Genomics Consortium.]]
 [[Category: amino-acid biosynthesis]]
 [[Category: arginine biosynthesis]]
@@ Line 35: / Line 35: @@
 [[Category: transcription regulation]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 11:00:34 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:07:38 2008''