Structural Biology: Difference between revisions
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[[Image:373px-X ray diffraction.png| | [[Image:373px-X ray diffraction.png|250px|right|thumb| The Steps toward Elucidating the Structure of Biological Macromolecules.]] | ||
[[Structural Biology]] is a branch of molecular biology & biochemistry concerned with the the molecular structure of biological macromolecules like proteins and [[Nucleic Acids|nucleic acids]]. It focuses on determining the structure of macromolecules to better understand their function and how to manipulate these macromolecules to develop therapeutics and broaden our understanding of biological phenomena. | [[Structural Biology]] is a branch of molecular biology & biochemistry concerned with the the molecular structure of biological macromolecules like proteins and [[Nucleic Acids|nucleic acids]]. It focuses on determining the structure of macromolecules to better understand their function and how to manipulate these macromolecules to develop therapeutics and broaden our understanding of biological phenomena. | ||
{{#tree:id=SBTopic|openlevels=1|close=top|open=top| | {{#tree:id=SBTopic|openlevels=1|close=top|open=top| | ||
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* [[About Macromolecular Structure|Macromolecular Structure Index]] | * [[About Macromolecular Structure|Macromolecular Structure Index]] | ||
* Methods of Structure Determination | * Methods of Structure Determination | ||
** NMR | |||
*** [[NMR Ensembles of Models]] | |||
** X-Ray Crystallography | ** X-Ray Crystallography | ||
*** [[Asymmetric Unit]] | *** [[Asymmetric Unit]] | ||
*** [[Biological Unit]] | *** [[Biological Unit]] | ||
*** [[Electron density maps]] | *** [[Electron density maps]] | ||
*** [[X-ray crystallography]] | |||
*** [[ | |||
* Methods of Structure & Sequence Analysis | * Methods of Structure & Sequence Analysis | ||
** Structural Analysis & Visualization | ** Structural Analysis & Visualization | ||
*** [[Chime]] | |||
*** [[CPK]] - Corey-Pauling-Koltun spacefilling molecular models and color scheme for elements | *** [[CPK]] - Corey-Pauling-Koltun spacefilling molecular models and color scheme for elements | ||
*** [[ | *** [[DRuMS]] - set of standard color schemes for macromolecular visualization | ||
*** [[User:Wayne Decatur/Generate Unfolded Structures|Generate Unfolded Structures]] | |||
*** [[User:Wayne Decatur/Teaching Proteopedia|Teaching Proteopedia]] | *** [[User:Wayne Decatur/Teaching Proteopedia|Teaching Proteopedia]] | ||
*** Homology Model | *** Homology Model | ||
**** [[User:Wayne Decatur/Homology Modeling|Homology Modeling]] | **** [[User:Wayne Decatur/Homology Modeling|Homology Modeling]] | ||
**** [[User:Emi Nakayama/TRIM5a Homology Models|TRIM5a Homology Models]] - Differences in models as a function of their templates | **** [[User:Emi Nakayama/TRIM5a Homology Models|TRIM5a Homology Models]] - Differences in models as a function of their templates | ||
*** [[ | *** Jmol | ||
**** [[FirstGlance in Jmol]] | |||
**** [[S347/Visualising protein structure|Visualising Protein Structure]] - Introduction to Jmol | |||
** Sequence Analysis | ** Sequence Analysis | ||
*** [[User:Wayne Decatur/Sequence analysis tools|Sequence Analysis Tools]] | *** [[User:Wayne Decatur/Sequence analysis tools|Sequence Analysis Tools]] | ||
}} | }} | ||
To view automatically seeded indices concerning Nucleic Acids See: | |||
*[[: Category:Macromolecule|Macromolecule]] | |||
*[[: Category:Nmr|NMR]] | |||
*[[:Category:Structure|Structure]] | |||
*[[: Category:X-ray|X-Ray]] | |||
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