3mdm: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3mdm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MDM OCA]. | |||
==Reference== | ==Reference== | ||
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[[Category: Thioperamide]] | [[Category: Thioperamide]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
Revision as of 00:44, 15 March 2011
Thioperamide complex of Cytochrome P450 46A1
Template:ABSTRACT PUBMED 20667828
About this Structure
3mdm is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Mast N, Charvet C, Pikuleva IA, Stout CD. Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain. J Biol Chem. 2010 Oct 8;285(41):31783-95. Epub 2010 Jul 28. PMID:20667828 doi:10.1074/jbc.M110.143313
- Mast N, White MA, Bjorkhem I, Johnson EF, Stout CD, Pikuleva IA. Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9546-51. Epub 2008 Jul 9. PMID:18621681
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Cholesterol 24-hydroxylase
- Homo sapiens
- Charvet, C.
- Mast, N.
- Pikuleva, I.
- Stout, C D.
- Cholesterol metabolism
- Cyp46a1
- Endoplasmic reticulum
- Heme
- Iron
- Lipid metabolism
- Membrane
- Metabolic enzyme
- Metal-binding
- Microsome
- Monooxygenase
- Nadp
- Oxidoreductase
- P450
- P450 46a1
- Steroid metabolism
- Thioperamide
- Transmembrane
