Neuroligin: Difference between revisions
New page: left|200px|thumb|Crystal Structure of human Neuroligin [[3be8]] {{STRUCTURE_3be8| PDB=3be8 | SIZE=300| SCENE= |right|CAPTION=Neuroligin 3be8 }} |
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[[Image:3be8a.png|left|200px|thumb|Crystal Structure of human Neuroligin [[3be8]]]] | [[Image:3be8a.png|left|200px|thumb|Crystal Structure of human Neuroligin [[3be8]]]] | ||
{{STRUCTURE_3be8| PDB=3be8 | SIZE=300| SCENE= |right|CAPTION=Neuroligin [[3be8]] }} | {{STRUCTURE_3be8| PDB=3be8 | SIZE=300| SCENE=Neuroligin/Cv/1 |right|CAPTION=Neuroligin [[3be8]] }} | ||
[[Neuroligin|Neuroligins]] (NLGN) are a family of postsynaptic proteins which bind to the presynaptic neurexin (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4. The images at the left and at the right correspond to one representative NLGN, ''i.e.'' the crystal structure of human Neuroligin ([[3be8]]). | |||
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== 3D Structures of Neuroligin == | |||
=== NLGN === | |||
[[3bl8]] - mNLGN-2 cholinesterase domain – mouse<br /> | |||
[[3be8]] - hNLGN-4 cholinesterase domain – human<br /> | |||
[[3bix]] - rNLGN-1 cholinesterase domain - rat<br /> | |||
=== NLGN+NRXN === | |||
[[2xb6]], [[2wqz]] – hNLGN-4 cholinesterase domain+NRXN-1β LNS domain <br /> | |||
[[3b3q]] - mNLGN-4 cholinesterase domain+NRXN-1β LNS domain<br /> | |||
[[3biw]] - rNLGN-1 cholinesterase domain+NRXN-1β LNS domain<br /> | |||
Revision as of 13:42, 13 October 2010
Neuroligins (NLGN) are a family of postsynaptic proteins which bind to the presynaptic neurexin (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4. The images at the left and at the right correspond to one representative NLGN, i.e. the crystal structure of human Neuroligin (3be8).
3D Structures of Neuroligin
NLGN
3bl8 - mNLGN-2 cholinesterase domain – mouse
3be8 - hNLGN-4 cholinesterase domain – human
3bix - rNLGN-1 cholinesterase domain - rat
NLGN+NRXN
2xb6, 2wqz – hNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3b3q - mNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3biw - rNLGN-1 cholinesterase domain+NRXN-1β LNS domain
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, David Canner, Pascale Marchot, Jaime Prilusky, Joel L. Sussman
