3km8: Difference between revisions

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{{Seed}}
[[Image:3km8.jpg|left|200px]]
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{{STRUCTURE_3km8|  PDB=3km8  |  SCENE=  }}  
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===Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine===
===Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine===


==Function==
[[http://www.uniprot.org/uniprot/ADA_MOUSE ADA_MOUSE]] Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (By similarity).


==About this Structure==
==About this Structure==
3KM8 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KM8 OCA].  
[[3km8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KM8 OCA].  
[[Category: Adenosine deaminase]]
[[Category: Adenosine deaminase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Nucleotide metabolism]]
[[Category: Nucleotide metabolism]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 20 06:36:10 2010''