3mvm: Difference between revisions

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{{Seed}}
[[Image:3mvm.png|left|200px]]
[[Image:3mvm.png|left|200px]]


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{{STRUCTURE_3mvm|  PDB=3mvm  |  SCENE=  }}  
{{STRUCTURE_3mvm|  PDB=3mvm  |  SCENE=  }}  


===P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V===
===P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V===


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{{ABSTRACT_PUBMED_20804198}}
{{ABSTRACT_PUBMED_20804198}}


==About this Structure==
==About this Structure==
3MVM is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MVM OCA].  
[[3mvm]] is a 2 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MVM OCA].  
 
==See Also==
*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20804198</ref><references group="xtra"/>
<ref group="xtra">PMID:020804198</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Transferase-transferase inhibitor complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 27 11:27:21 2010''

Revision as of 14:51, 26 July 2012

File:3mvm.png

Template:STRUCTURE 3mvm

P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V

Template:ABSTRACT PUBMED 20804198

About this Structure

3mvm is a 2 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Liu C, Lin J, Wrobleski ST, Lin S, Hynes J, Wu H, Dyckman AJ, Li T, Wityak J, Gillooly KM, Pitt S, Shen DR, Zhang RF, McIntyre KW, Salter-Cid L, Shuster DJ, Zhang H, Marathe PH, Doweyko AM, Sack JS, Kiefer SE, Kish KF, Newitt JA, McKinnon M, Dodd JH, Barrish JC, Schieven GL, Leftheris K. Discovery of 4-(5-(cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[ 1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a clinical p38alpha MAP kinase inhibitor for the treatment of inflammatory diseases. J Med Chem. 2010 Sep 23;53(18):6629-39. PMID:20804198 doi:10.1021/jm100540x

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