3m45: Difference between revisions

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{{Seed}}
[[Image:3m45.png|left|200px]]
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{{STRUCTURE_3m45|  PDB=3m45  |  SCENE=  }}  
{{STRUCTURE_3m45|  PDB=3m45  |  SCENE=  }}  
===Crystal structure of Ig1 domain of mouse SynCAM 2===
===Crystal structure of Ig1 domain of mouse SynCAM 2===
{{ABSTRACT_PUBMED_20739279}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/CADM2_MOUSE CADM2_MOUSE]] Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes (By similarity).
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{{ABSTRACT_PUBMED_20739279}}


==About this Structure==
==About this Structure==
3M45 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M45 OCA].  
[[3m45]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M45 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20739279</ref><references group="xtra"/>
<ref group="xtra">PMID:020739279</ref><references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Modis, Y.]]
[[Category: Modis, Y.]]
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[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 18 00:22:36 2010''

Revision as of 23:25, 10 April 2013

Template:STRUCTURE 3m45

Crystal structure of Ig1 domain of mouse SynCAM 2

Template:ABSTRACT PUBMED 20739279

Function

[CADM2_MOUSE] Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes (By similarity).

About this Structure

3m45 is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Fogel AI, Li Y, Giza J, Wang Q, Lam TT, Modis Y, Biederer T. N-glycosylation at the SynCAM immunoglobulin interface modulates synaptic adhesion. J Biol Chem. 2010 Aug 25. PMID:20739279 doi:10.1074/jbc.M110.120865

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