3ntb: Difference between revisions
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{{STRUCTURE_3ntb| PDB=3ntb | SCENE= }} | {{STRUCTURE_3ntb| PDB=3ntb | SCENE= }} | ||
===Structure of 6-methylthio naproxen analog bound to mCOX-2.=== | ===Structure of 6-methylthio naproxen analog bound to mCOX-2.=== | ||
{{ABSTRACT_PUBMED_20810665}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/Q543K3_MOUSE Q543K3_MOUSE]] Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.<ref>PMID:12925531</ref> <ref>PMID:20463020</ref> <ref>PMID:20810665</ref> <ref>PMID:21489986</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3ntb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NTB OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020810665</ref><references group="xtra"/><references/> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Prostaglandin-endoperoxide synthase]] | [[Category: Prostaglandin-endoperoxide synthase]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Prostaglandin h2 synthase]] | [[Category: Prostaglandin h2 synthase]] | ||