3lpf: Difference between revisions

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{{Seed}}
[[Image:3lpf.jpg|left|200px]]
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{{STRUCTURE_3lpf|  PDB=3lpf  |  SCENE=  }}  
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===Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 1-((6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea===
===Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 1-((6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea===
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{{ABSTRACT_PUBMED_21051639}}
{{ABSTRACT_PUBMED_21051639}}


==About this Structure==
==About this Structure==
3LPF is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LPF OCA].  
[[3lpf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LPF OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:21051639</ref><references group="xtra"/>
<ref group="xtra">PMID:021051639</ref><references group="xtra"/><references/>
[[Category: Beta-glucuronidase]]
[[Category: Beta-glucuronidase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Sugar-binding domain]]
[[Category: Sugar-binding domain]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 18 00:49:41 2010''

Revision as of 23:08, 10 April 2013

Template:STRUCTURE 3lpf

Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 1-((6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea

Template:ABSTRACT PUBMED 21051639

About this Structure

3lpf is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Wallace BD, Wang H, Lane KT, Scott JE, Orans J, Koo JS, Venkatesh M, Jobin C, Yeh LA, Mani S, Redinbo MR. Alleviating cancer drug toxicity by inhibiting a bacterial enzyme. Science. 2010 Nov 5;330(6005):831-5. PMID:21051639 doi:10.1126/science.1191175

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