3phn: Difference between revisions
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{{STRUCTURE_3phn| PDB=3phn | SCENE= }} | {{STRUCTURE_3phn| PDB=3phn | SCENE= }} | ||
===Crystal structure of wild-type onconase with resolution 1.46 A=== | ===Crystal structure of wild-type onconase with resolution 1.46 A=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/RNP30_RANPI RNP30_RANPI]] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA. | |||
==About this Structure== | ==About this Structure== | ||
[[3phn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rana_pipiens Rana pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHN OCA]. | |||
[[Category: Rana pipiens]] | [[Category: Rana pipiens]] | ||
[[Category: Kurpiewska, K.]] | [[Category: Kurpiewska, K.]] | ||
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[[Category: Protein p-30]] | [[Category: Protein p-30]] | ||
[[Category: Ranpirnase]] | [[Category: Ranpirnase]] | ||