3m3e: Difference between revisions
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{{STRUCTURE_3m3e| PDB=3m3e | SCENE= }} | {{STRUCTURE_3m3e| PDB=3m3e | SCENE= }} | ||
===Crystal Structure of Agrocybe aegerita lectin AAL mutant E66A complexed with p-Nitrophenyl Thomsen-Friedenreich disaccharide=== | ===Crystal Structure of Agrocybe aegerita lectin AAL mutant E66A complexed with p-Nitrophenyl Thomsen-Friedenreich disaccharide=== | ||
{{ABSTRACT_PUBMED_20530247}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ATLE_AGRAE ATLE_AGRAE]] Anti-tumor lectin with DNase activity. Inhibits the growth of several tumor cell lines in vitro. Induces lymphocyte infiltration and necrosis of tumor cells in a mouse tumor model. Induces apoptosis in HeLa cells.<ref>PMID:12757412</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3m3e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrocybe_aegerita Agrocybe aegerita]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M3E OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020530247</ref><references group="xtra"/><references/> | ||
[[Category: Agrocybe aegerita]] | [[Category: Agrocybe aegerita]] | ||
[[Category: Feng, L.]] | [[Category: Feng, L.]] | ||
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[[Category: Nuclease]] | [[Category: Nuclease]] | ||
[[Category: Thomsen-friedenreich disaccharide]] | [[Category: Thomsen-friedenreich disaccharide]] | ||