Indinavir: Difference between revisions

Revision as of 18:52, 1 December 2010

Marketed By:
Major Indication: Human Immunodeficiency Virus Infection
Drug Class: HIV Protease Inhibitor
Date of FDA Approval (Patent Expiration):
2006 Sales:
Importance:
The following is a list of Pharmacokinetic Parameters. See: Pharmaceutical Drugs for more information

HIV Protease Inhibitor Pharmacokinetics
Parameter	Ritonavir	Tipranavir	Indinavir	Saquinavir	Amprenavir	Lopinavir	Ritonavir	Darunavir	Atazanavir	Nelfinavir
T_max (hr)	Ritonavir	Tipranavir	Indinavir	Saquinavir	Amprenavir	Lopinavir	Ritonavir	Darunavir	Atazanavir	Nelfinavir
C_max (ng/ml)	Ritonavir	Tipranavir	Indinavir	Saquinavir	Amprenavir	Lopinavir	Ritonavir	Darunavir	Atazanavir	Nelfinavir
Bioavailability (%)	Ritonavir	Tipranavir	Indinavir	Saquinavir	Amprenavir	Lopinavir	Ritonavir	Darunavir	Atazanavir	Nelfinavir
Protein Binding (%)	Ritonavir	Tipranavir	Indinavir	Saquinavir	Amprenavir	Lopinavir	Ritonavir	Darunavir	Atazanavir	Nelfinavir
T_1/2 (hr)	Ritonavir	Tipranavir	Indinavir	Saquinavir	Amprenavir	Lopinavir	Ritonavir	Darunavir	Atazanavir	Nelfinavir
AUC (ng/ml/hr)	Ritonavir	Tipranavir	Indinavir	Saquinavir	Amprenavir	Lopinavir	Ritonavir	Darunavir	Atazanavir	Nelfinavir
IC₅₀ (nM)	Ritonavir	Tipranavir	Indinavir	Saquinavir	Amprenavir	Lopinavir	Ritonavir	Darunavir	Atazanavir	Nelfinavir
Dosage (mg)	Ritonavir	Tipranavir	Indinavir	Saquinavir	Amprenavir	Lopinavir	Ritonavir	Darunavir	Atazanavir	Nelfinavir
Metabolism	Ritonavir	Tipranavir	Indinavir	Saquinavir	Amprenavir	Lopinavir	Ritonavir	Darunavir	Atazanavir	Nelfinavir

@@ Line 16: / Line 16: @@
 |-
 ! Parameter
-! Ritonavir
+! [[Ritonavir]]
-! Tipranavir
+! [[Tipranavir]]
-! Indinavir
+! [[Indinavir]]
-! Saquinavir
+! [[Saquinavir]]
-! Amprenavir
+! [[Amprenavir]]
-! Lopinavir
+! [[Lopinavir]]
-! Ritonavir
+! [[Ritonavir]]
-! Darunavir
+! [[Darunavir]]
-! Atazanavir
+! [[Atazanavir]]
-! Nelfinavir
+! [[Nelfinavir]]
 |-
 ! [[Pharmaceutical_Drugs#Tmax|T<sub>max</sub>]] (hr)