Colicin: Difference between revisions

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==Targeting and Receptors==
==Targeting and Receptors==


Colicins vary significantly in the receptors that they target to initiate their uptake. The majority of the group A colicins use the BtuB receptor, which is present on ''E. coli'' as a vitamin B12 uptake receptor.


==Colicin Uptake==
==Colicin Uptake==


Colicins are divided into two groups depending on the method of uptake which they target. Group A colicins use the Tol system to bind to and enter the target cell, and group B use the Ton system.


==Killing Activities==
==Killing Activities==
The killing activities carried out by colicins could be used medicinally as an alternative to antibiotics in the case where the specific strain of ''E. coli'' can be identified. <ref> PMID: 17724148 </ref>