Colicin A: Difference between revisions
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==Uptake== | ==Uptake== | ||
Colicin A binds to the BtuB Vitamin B12 outer membrane receptor of the target cell, and uses the [[Tol]] system to translocate across the membrane, specifically TolQRAB, alongside the OmpF protein. Its use of the Tol system means that Colicin A is in the A group of colicins. | Colicin A binds to the BtuB Vitamin B12 outer membrane receptor of the target cell, and uses the [[Tol]] system to translocate across the membrane, specifically TolQRAB, alongside the OmpF protein. Its use of the Tol system means that Colicin A is in the A group of colicins. | ||
{{STRUCTURE_3iax | PDB=3iax | SCENE= }} | |||
This structure shows the TolB box of colA bound to TolB. | |||
==Cytotoxic activity== | ==Cytotoxic activity== | ||
