Gefitinib: Difference between revisions

From Proteopedia
Jump to navigationJump to search
David Canner (talk | contribs)
No edit summary
David Canner (talk | contribs)
No edit summary
Line 9: Line 9:
* The following is a list of Pharmacokinetic Parameters. See: [[Pharmaceutical Drugs]] for more information
* The following is a list of Pharmacokinetic Parameters. See: [[Pharmaceutical Drugs]] for more information
===Mechanism of Action===
===Mechanism of Action===
[[EGFR|Epidermal Growth Factor Receptors]] are overexpressed  
[[EGFR|Epidermal Growth Factor Receptors]] are overexpressed in many types of human [[Cancer|carcinomas]] including lung, pancreatic, and breast cancer. This overexpression leads to excessive activation of the anti-apoptotic [[Ras]] signalling cascade.


===Pharmacokinetics===
===Pharmacokinetics===