3lra: Difference between revisions
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{{STRUCTURE_3lra| PDB=3lra | SCENE= }} | {{STRUCTURE_3lra| PDB=3lra | SCENE= }} | ||
===Structural Basis for Assembling a Human Tripartite Complex Dlg1-MPP7-Mals3=== | ===Structural Basis for Assembling a Human Tripartite Complex Dlg1-MPP7-Mals3=== | ||
{{ABSTRACT_PUBMED_20702775}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DLG1_HUMAN DLG1_HUMAN]] Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel.<ref>PMID:10656683</ref> <ref>PMID:12445884</ref> <ref>PMID:14699157</ref> <ref>PMID:15263016</ref> <ref>PMID:19213956</ref> <ref>PMID:20605917</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3lra]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LRA OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020702775</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Long, J.]] | [[Category: Long, J.]] | ||
| Line 44: | Line 31: | ||
[[Category: Transport]] | [[Category: Transport]] | ||
[[Category: Tripartite complex]] | [[Category: Tripartite complex]] | ||