3pjc: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:3pjc.jpg|left|200px]] | |||
The | <!-- | ||
The line below this paragraph, containing "STRUCTURE_3pjc", creates the "Structure Box" on the page. | |||
You may change the PDB parameter (which sets the PDB file loaded into the applet) | |||
or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |||
or leave the SCENE parameter empty for the default display. | |||
--> | |||
{{STRUCTURE_3pjc| PDB=3pjc | SCENE= }} | |||
===Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family=== | |||
<!-- | |||
The line below this paragraph, {{ABSTRACT_PUBMED_21155605}}, adds the Publication Abstract to the page | |||
(as it appears on PubMed at http://www.pubmed.gov), where 21155605 is the PubMed ID number. | |||
--> | |||
{{ABSTRACT_PUBMED_21155605}} | |||
==About this Structure== | |||
[[3pjc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJC OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:21155605</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Non-specific protein-tyrosine kinase]] | |||
[[Category: Kroemer, M.]] | |||
[[Category: Tavares, G A.]] | |||
[[Category: Thoma, G.]] | |||
[[Category: Zerwes, H G.]] | |||
[[Category: Atp site kinase inhibitor]] | |||
[[Category: Atp-binding]] | |||
[[Category: Small molecule inhibitor]] | |||
[[Category: Transferase]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
Revision as of 18:40, 29 December 2010
Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family
Template:ABSTRACT PUBMED 21155605
About this Structure
3pjc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Thoma G, Nuninger F, Falchetto R, Hermes E, Tavares GA, Vangrevelinghe E, Zerwes HG. Identification of a Potent Janus Kinase 3 Inhibitor with High Selectivity within the Janus Kinase Family. J Med Chem. 2010 Dec 14. PMID:21155605 doi:10.1021/jm101157q