3nsj: Difference between revisions

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{{Seed}}
[[Image:3nsj.png|left|200px]]
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{{STRUCTURE_3nsj|  PDB=3nsj  |  SCENE=  }}  
{{STRUCTURE_3nsj|  PDB=3nsj  |  SCENE=  }}  
===The X-ray crystal structure of lymphocyte perforin===
===The X-ray crystal structure of lymphocyte perforin===
{{ABSTRACT_PUBMED_21037563}}


 
==Function==
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[[http://www.uniprot.org/uniprot/PERF_MOUSE PERF_MOUSE]] Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.<ref>PMID:3261391</ref> <ref>PMID:8164737</ref> <ref>PMID:7526382</ref> <ref>PMID:19446473</ref> <ref>PMID:21037563</ref>
The line below this paragraph, {{ABSTRACT_PUBMED_21037563}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 21037563 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21037563}}


==About this Structure==
==About this Structure==
3NSJ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NSJ OCA].  
[[3nsj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NSJ OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:21037563</ref><references group="xtra"/>
<ref group="xtra">PMID:021037563</ref><references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Caradoc-Davies, T T.]]
[[Category: Caradoc-Davies, T T.]]
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[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Pore forming protein]]
[[Category: Pore forming protein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:12:16 2010''