3pup: Difference between revisions

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New page: '''Unreleased structure''' The entry 3pup is ON HOLD Authors: Filippakopoulos, P., Kraling, K., Essen, L.O., Meggers, E., Knapp, S. Description: Structure of Glycogen Synthase Kinase 3...
 
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'''Unreleased structure'''
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[[Image:3pup.jpg|left|200px]]


The entry 3pup is ON HOLD
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{{STRUCTURE_3pup|  PDB=3pup |  SCENE=  }}


Authors: Filippakopoulos, P., Kraling, K., Essen, L.O., Meggers, E., Knapp, S.
===Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1)===


Description: Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1)


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:25:43 2010''
==About this Structure==
3PUP is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PUP OCA].
 
==Reference==
<ref group="xtra">PMID:18973295</ref><ref group="xtra">PMID:19035373</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Essen, L O.]]
[[Category: Filippakopoulos, P.]]
[[Category: Knapp, S.]]
[[Category: Kraling, K.]]
[[Category: Meggers, E.]]
[[Category: Atp-binding]]
[[Category: Kinase]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Ruthenium glycogen synthase kinase picomolar]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Wnt signaling pathway]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 10:02:51 2010''

Revision as of 06:50, 22 December 2010

File:3pup.jpg

Template:STRUCTURE 3pup

Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1)

About this Structure

3PUP is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Maksimoska J, Feng L, Harms K, Yi C, Kissil J, Marmorstein R, Meggers E. Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes. J Am Chem Soc. 2008 Nov 26;130(47):15764-5. PMID:18973295 doi:10.1021/ja805555a
  2. Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3. Chembiochem. 2008 Dec 15;9(18):2933-6. PMID:19035373 doi:10.1002/cbic.200800489

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