Disintegrin: Difference between revisions
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New page: left|200px|thumb|Crystal Structure of Disintegrin [[1z1x]] {{STRUCTURE_1z1x| PDB=1z1x | SIZE=300| SCENE= |right|CAPTION=Disintegrin 1z1x }} |
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[[Image:1z1x.png|left|200px|thumb|Crystal Structure of Disintegrin [[1z1x]]]] | [[Image:1z1x.png|left|200px|thumb|Crystal Structure of Disintegrin [[1z1x]]]] | ||
{{STRUCTURE_1z1x| PDB=1z1x | SIZE=300| SCENE= |right|CAPTION=Disintegrin [[1z1x]] }} | {{STRUCTURE_1z1x| PDB=1z1x | SIZE=300| SCENE=Disintegrin/Cv/1 |right|CAPTION=Disintegrin [[1z1x]] }} | ||
[[Disintegrin|Disintegrins]] are a family of toxins from viper venoms which inhibit platelet aggregation and cell adhesion. The images at the left and at the right correspond to one representative Disintegrin, ''i.e.'' the crystal structure of Disintegrin from ''Echis carinatus'' ([[1z1x]]). | |||
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== 3D Structures of Disintegrin == | |||
[[2w9o]], [[2w9u]], [[2w9v]], [[2w9w]] – jerdostatin residues 68-110 – ''Trimeresurus jerdonii'' – NMR<br /> | |||
[[1j2l]] – trimestatin - ''Trimeresurus flavovidrius''<br /> | |||
[[2pjf]], [[1q7i]], [[1q7j]] – Cr rhodostoxin residues 1-68 – ''Calloselasma rhodostoma'' – NMR<br /> | |||
[[2pjg]], [[2pji]] - Cr rhodostoxin (mutant) – NMR<br /> | |||
[[1z1x]], [[1tej]] – Ec disintegrin – ''Echis carinatus''<br /> | |||
[[1rmr]] – Ec schistatin<br /> | |||
[[1ro3]], [[2ech]] – Ec echistatin - NMR<br /> | |||
[[1l3x]] – salmosin – ''Gloydius brevicaudus'' – NMR<br /> | |||
[[1mpz]] – obtustatin – ''Macrovipera obtusa'' - NMR<br /> | |||
[[1dem]] – dendrotoxin I – black mamba<br /> | |||
[[1den]] - dendrotoxin I - NMR<br /> | |||
[[1dtk]] - dendrotoxin K- NMR<br /> | |||
[[1dtx]] – α-dendrotoxin - Eastern green mamba<br /> | |||