3k45: Difference between revisions
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[[Image:3k45.png|left|200px]] | [[Image:3k45.png|left|200px]] | ||
{{STRUCTURE_3k45| PDB=3k45 | SCENE= }} | {{STRUCTURE_3k45| PDB=3k45 | SCENE= }} | ||
===Alternate Binding Modes Observed for the E- and Z-isomers of 2,4-Diaminofuro[2,3d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase=== | ===Alternate Binding Modes Observed for the E- and Z-isomers of 2,4-Diaminofuro[2,3d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase=== | ||
{{ABSTRACT_PUBMED_19748785}} | {{ABSTRACT_PUBMED_19748785}} | ||
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==See Also== | ==See Also== | ||
*[[Dihydrofolate reductase]] | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019748785</ref><references group="xtra"/> | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
Revision as of 10:19, 27 July 2012
Alternate Binding Modes Observed for the E- and Z-isomers of 2,4-Diaminofuro[2,3d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase
Template:ABSTRACT PUBMED 19748785
About this Structure
3k45 is a 1 chain structure of Dihydrofolate reductase with sequence from Mus musculus. Full crystallographic information is available from OCA.
See Also
Reference
- Gangjee A, Li W, Lin L, Zeng Y, Ihnat M, Warnke LA, Green DW, Cody V, Pace J, Queener SF. Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors. Bioorg Med Chem. 2009 Oct 15;17(20):7324-36. Epub 2009 Aug 22. PMID:19748785 doi:10.1016/j.bmc.2009.08.044
