2kfx: Difference between revisions

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[[Image:2kfx.png|left|200px]]
[[Image:2kfx.png|left|200px]]


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{{STRUCTURE_2kfx|  PDB=2kfx  |  SCENE=  }}  
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===Structure of the N-terminal domain of human cardiac troponin C bound to calcium ion and to the inhibitor W7===
===Structure of the N-terminal domain of human cardiac troponin C bound to calcium ion and to the inhibitor W7===


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{{ABSTRACT_PUBMED_19419198}}
{{ABSTRACT_PUBMED_19419198}}


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==See Also==
==See Also==
*[[Troponin]]
*[[Troponin|Troponin]]


==Reference==
==Reference==
<ref group="xtra">PMID:19419198</ref><ref group="xtra">PMID:10387074</ref><ref group="xtra">PMID:12060657</ref><references group="xtra"/>
<ref group="xtra">PMID:019419198</ref><ref group="xtra">PMID:010387074</ref><ref group="xtra">PMID:012060657</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hoffman, R M.B.]]
[[Category: Hoffman, R M.B.]]
[[Category: Sykes, B D.]]
[[Category: Sykes, B D.]]
[[Category: Acetylation]]
[[Category: Calcium]]
[[Category: Calcium regulation]]
[[Category: Calcium regulation]]
[[Category: Cardiac]]
[[Category: Cardiac]]
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[[Category: Metal binding protein]]
[[Category: Metal binding protein]]
[[Category: Muscle protein]]
[[Category: Muscle protein]]
[[Category: Polymorphism]]
[[Category: Striated muscle]]
[[Category: Striated muscle]]
[[Category: Troponin]]
[[Category: Troponin]]
[[Category: W7]]
[[Category: W7]]

Revision as of 06:52, 26 July 2012

File:2kfx.png

Template:STRUCTURE 2kfx

Structure of the N-terminal domain of human cardiac troponin C bound to calcium ion and to the inhibitor W7

Template:ABSTRACT PUBMED 19419198

About this Structure

2kfx is a 1 chain structure of Troponin with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

Reference

  1. Hoffman RM, Sykes BD. Structure of the Inhibitor W7 Bound to the Regulatory Domain of Cardiac Troponin C. Biochemistry. 2009 May 21. PMID:19419198 doi:10.1021/bi9001826
  2. Li MX, Spyracopoulos L, Sykes BD. Binding of cardiac troponin-I147-163 induces a structural opening in human cardiac troponin-C. Biochemistry. 1999 Jun 29;38(26):8289-98. PMID:10387074 doi:10.1021/bi9901679
  3. Wang X, Li MX, Sykes BD. Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridil. J Biol Chem. 2002 Aug 23;277(34):31124-33. Epub 2002 Jun 11. PMID:12060657 doi:10.1074/jbc.M203896200

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