3fre: Difference between revisions

Revision as of 10:57, 27 July 2012

3fre is a 1 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Oefner C, Bandera M, Haldimann A, Laue H, Schulz H, Mukhija S, Parisi S, Weiss L, Lociuro S, Dale GE. Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity. J Antimicrob Chemother. 2009 Apr;63(4):687-98. Epub 2009 Feb 11. PMID:19211577 doi:10.1093/jac/dkp024

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 [[Image:3fre.png|left|200px]]
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 {{STRUCTURE_3fre|  PDB=3fre  |  SCENE=  }}
 ===S. aureus DHFR complexed with NADPH and TMP===
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 ==See Also==
-*[[Dihydrofolate reductase]]
+*[[Dihydrofolate reductase|Dihydrofolate reductase]]
 ==Reference==
-<ref group="xtra">PMID:19211577</ref><references group="xtra"/>
+<ref group="xtra">PMID:019211577</ref><references group="xtra"/>
 [[Category: Dihydrofolate reductase]]
 [[Category: Staphylococcus aureus]]