3gpt: Difference between revisions

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[[Image:3gpt.png|left|200px]]
[[Image:3gpt.png|left|200px]]


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{{STRUCTURE_3gpt|  PDB=3gpt  |  SCENE=  }}  
{{STRUCTURE_3gpt|  PDB=3gpt  |  SCENE=  }}  


===Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligand===
===Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligand===


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{{ABSTRACT_PUBMED_19678642}}
{{ABSTRACT_PUBMED_19678642}}


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==See Also==
==See Also==
*[[Proteasome]]
*[[Jmol/Visualizing large molecules|Jmol/Visualizing large molecules]]
*[[Proteasome|Proteasome]]


==Reference==
==Reference==
<ref group="xtra">PMID:19678642</ref><references group="xtra"/>
<ref group="xtra">PMID:019678642</ref><references group="xtra"/>
[[Category: Proteasome endopeptidase complex]]
[[Category: Proteasome endopeptidase complex]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Potts, C B.]]
[[Category: Potts, C B.]]
[[Category: Cancer therapy]]
[[Category: Cancer therapy]]
[[Category: Cytoplasm]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Immunology]]
[[Category: Immunology]]
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[[Category: Time dependent leaving group elimination]]
[[Category: Time dependent leaving group elimination]]
[[Category: Ubiquitin]]
[[Category: Ubiquitin]]
[[Category: Ubl conjugation]]
[[Category: Zymogen]]
[[Category: Zymogen]]

Revision as of 17:22, 25 July 2012

File:3gpt.png

Template:STRUCTURE 3gpt

Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligand

Template:ABSTRACT PUBMED 19678642

About this Structure

3gpt is a 28 chain structure of Proteasome with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

See Also

Reference

  1. Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC. Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition. J Med Chem. 2009 Sep 10;52(17):5420-8. PMID:19678642 doi:10.1021/jm900559x

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