2qoe: Difference between revisions

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==Overview==
==Overview==
Various beta-amino amides containing triazolopiperazine heterocycles have, been prepared and evaluated as potent, selective, orally active dipeptidyl, peptidase IV (DPP-4) inhibitors. These compounds display excellent oral, bioavailability and good overall pharmacokinetic profiles in preclinical, species. Moreover, in vivo efficacy in an oral glucose tolerance test in, lean mice is demonstrated.
Various beta-amino amides containing triazolopiperazine heterocycles have been prepared and evaluated as potent, selective, orally active dipeptidyl peptidase IV (DPP-4) inhibitors. These compounds display excellent oral bioavailability and good overall pharmacokinetic profiles in preclinical species. Moreover, in vivo efficacy in an oral glucose tolerance test in lean mice is demonstrated.


==About this Structure==
==About this Structure==
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[[Category: transmembrane]]
[[Category: transmembrane]]


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