1ghw: Difference between revisions

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[[Image:1ghw.png|left|200px]]
[[Image:1ghw.png|left|200px]]


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{{STRUCTURE_1ghw|  PDB=1ghw  |  SCENE=  }}  
{{STRUCTURE_1ghw|  PDB=1ghw  |  SCENE=  }}  


===A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE===
===A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE===


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{{ABSTRACT_PUBMED_11292354}}
{{ABSTRACT_PUBMED_11292354}}


==About this Structure==
==About this Structure==
[[1ghw]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHW OCA].  
[[1ghw]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GHW OCA].  


==See Also==
==See Also==
*[[Hirudin]]
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:11292354</ref><references group="xtra"/>
<ref group="xtra">PMID:011292354</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Young, W.]]
[[Category: Young, W.]]
[[Category: Blood clotting]]
[[Category: Blood clotting]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Oxyanion hole water]]
[[Category: Oxyanion hole water]]
[[Category: Shift of pka of his57]]
[[Category: Shift of pka of his57]]

Revision as of 12:04, 27 July 2012

File:1ghw.png

Template:STRUCTURE 1ghw

A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE

Template:ABSTRACT PUBMED 11292354

About this Structure

1ghw is a 3 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Katz BA, Elrod K, Luong C, Rice MJ, Mackman RL, Sprengeler PA, Spencer J, Hataye J, Janc J, Link J, Litvak J, Rai R, Rice K, Sideris S, Verner E, Young W. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site. J Mol Biol. 2001 Apr 13;307(5):1451-86. PMID:11292354 doi:https://dx.doi.org/10.1006/jmbi.2001.4516

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