2iwx: Difference between revisions

Revision as of 05:30, 27 July 2012

2iwx is a 1 chain structure of Heat Shock Proteins with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Proisy N, Sharp SY, Boxall K, Connelly S, Roe SM, Prodromou C, Slawin AM, Pearl LH, Workman P, Moody CJ. Inhibition of Hsp90 with synthetic macrolactones: synthesis and structural and biological evaluation of ring and conformational analogs of radicicol. Chem Biol. 2006 Nov;13(11):1203-15. PMID:17114002 doi:10.1016/j.chembiol.2006.09.015

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 [[Image:2iwx.png|left|200px]]
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 {{STRUCTURE_2iwx|  PDB=2iwx  |  SCENE=  }}
 ===ANALOGUES OF RADICICOL BOUND TO THE ATP-BINDING SITE OF HSP90.===
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 ==See Also==
-*[[Heat Shock Proteins]]
+*[[Heat Shock Proteins|Heat Shock Proteins]]
 ==Reference==
-<ref group="xtra">PMID:17114002</ref><references group="xtra"/>
+<ref group="xtra">PMID:017114002</ref><references group="xtra"/>
 [[Category: Saccharomyces cerevisiae]]
 [[Category: Pearl, L H.]]
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 [[Category: Chaperone]]
 [[Category: Chaperone-complex]]
-[[Category: Chaperone/complex]]
 [[Category: Heat shock]]
 [[Category: Inhibitor]]
 [[Category: Multigene family]]
-[[Category: Nucleotide-binding]]
+[[Category: Nucleotide- binding]]