3d49: Difference between revisions

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[[Image:3d49.png|left|200px]]
[[Image:3d49.png|left|200px]]


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{{STRUCTURE_3d49|  PDB=3d49  |  SCENE=  }}  
{{STRUCTURE_3d49|  PDB=3d49  |  SCENE=  }}  


===Thrombin Inhibition===
===Thrombin Inhibition===


{{ABSTRACT_PUBMED_019409395}}


==About this Structure==
==About this Structure==
[[3d49]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D49 OCA].  
[[3d49]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D49 OCA].  


==See Also==
==See Also==
*[[Hirudin]]
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]
 
==Reference==
<ref group="xtra">PMID:019409395</ref><references group="xtra"/>
[[Category: Hirudo medicinalis]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Klebe, G.]]
[[Category: Klebe, G.]]
[[Category: Acute phase]]
[[Category: Acute phase]]
[[Category: Blood clotting-hydrolase inhibitor complex]]
[[Category: Blood clotting/hydrolase inhibitor]]
[[Category: Blood clotting/hydrolase inhibitor]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
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[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Kringle]]
[[Category: Kringle]]
[[Category: Pharmaceutical]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]

Revision as of 22:42, 26 July 2012

File:3d49.png

Template:STRUCTURE 3d49

Thrombin Inhibition

Template:ABSTRACT PUBMED 019409395

About this Structure

3d49 is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Baum B, Mohamed M, Zayed M, Gerlach C, Heine A, Hangauer D, Klebe G. More than a simple lipophilic contact: a detailed thermodynamic analysis of nonbasic residues in the s1 pocket of thrombin. J Mol Biol. 2009 Jul 3;390(1):56-69. Epub 2009 May 3. PMID:19409395 doi:10.1016/j.jmb.2009.04.051

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