1kmv: Difference between revisions

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[[Image:1kmv.png|left|200px]]
[[Image:1kmv.png|left|200px]]


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{{STRUCTURE_1kmv|  PDB=1kmv  |  SCENE=  }}  
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===HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND (Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE (SRI-9662), A LIPOPHILIC ANTIFOLATE===
===HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND (Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE (SRI-9662), A LIPOPHILIC ANTIFOLATE===


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{{ABSTRACT_PUBMED_12096917}}


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==See Also==
==See Also==
*[[Dihydrofolate reductase]]
*[[Dihydrofolate reductase|Dihydrofolate reductase]]


==Reference==
==Reference==
<ref group="xtra">PMID:12096917</ref><references group="xtra"/>
<ref group="xtra">PMID:012096917</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 23:00, 26 July 2012

File:1kmv.png

Template:STRUCTURE 1kmv

HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND (Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE (SRI-9662), A LIPOPHILIC ANTIFOLATE

Template:ABSTRACT PUBMED 12096917

About this Structure

1kmv is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Klon AE, Heroux A, Ross LJ, Pathak V, Johnson CA, Piper JR, Borhani DW. Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution. J Mol Biol. 2002 Jul 12;320(3):677-93. PMID:12096917

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