2anq: Difference between revisions
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[[Image:2anq.png|left|200px]] | [[Image:2anq.png|left|200px]] | ||
{{STRUCTURE_2anq| PDB=2anq | SCENE= }} | {{STRUCTURE_2anq| PDB=2anq | SCENE= }} | ||
===Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a.=== | ===Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a.=== | ||
{{ABSTRACT_PUBMED_17125251}} | {{ABSTRACT_PUBMED_17125251}} | ||
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==See Also== | ==See Also== | ||
*[[Dihydrofolate reductase]] | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017125251</ref><references group="xtra"/> | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
Revision as of 20:35, 25 July 2012
Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a.
Template:ABSTRACT PUBMED 17125251
About this Structure
2anq is a 1 chain structure of Dihydrofolate reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.
See Also
Reference
- Summerfield RL, Daigle DM, Mayer S, Mallik D, Hughes DW, Jackson SG, Sulek M, Organ MG, Brown ED, Junop MS. A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region. J Med Chem. 2006 Nov 30;49(24):6977-86. PMID:17125251 doi:10.1021/jm060570v