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[[Image:3ofc.png|left|200px]]
[[Image:3ofc.png|left|200px]]


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{{STRUCTURE_3ofc|  PDB=3ofc  |  SCENE=  }}  
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===Crystal structure of the E. coli ribosome bound to chloramphenicol. This file contains the 50S subunit of the first 70S ribosome with chloramphenicol bound.===
===Crystal structure of the E. coli ribosome bound to chloramphenicol. This file contains the 50S subunit of the first 70S ribosome with chloramphenicol bound.===


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{{ABSTRACT_PUBMED_20876128}}
{{ABSTRACT_PUBMED_20876128}}


==About this Structure==
==About this Structure==
[[3ofc]] is a 30 chain structure of [[Ribosomal protein L2]], [[Ribosomal protein L3]], [[Ribosomal protein L4]], [[Ribosomal protein L5]] and [[Ribosomal protein L6]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OFC OCA].  
[[3ofc]] is a 30 chain structure of [[Ribosomal protein L11]], [[Ribosomal protein L13]], [[Ribosomal protein L15]], [[Ribosomal protein L16]], [[Ribosomal protein L17]], [[Ribosomal protein L18]], [[Ribosomal protein L19]], [[Ribosomal protein L2]], [[Ribosomal protein L20]], [[Ribosomal protein L21]], [[Ribosomal protein L22]], [[Ribosomal protein L23]], [[Ribosomal protein L24]], [[Ribosomal protein L25]], [[Ribosomal protein L27]], [[Ribosomal protein L28]], [[Ribosomal protein L29]], [[Ribosomal protein L3]], [[Ribosomal protein L30]], [[Ribosomal protein L32]], [[Ribosomal protein L33]], [[Ribosomal protein L34]], [[Ribosomal protein L35]], [[Ribosomal protein L36]], [[Ribosomal protein L4]], [[Ribosomal protein L5]], [[Ribosomal protein L6]] and [[Ribosomal protein L9]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OFC OCA].  


==See Also==
==See Also==
*[[Ribosomal protein L2]]
*[[Ribosomal protein L11|Ribosomal protein L11]]
*[[Ribosomal protein L3]]
*[[Ribosomal protein L13|Ribosomal protein L13]]
*[[Ribosomal protein L4]]
*[[Ribosomal protein L15|Ribosomal protein L15]]
*[[Ribosomal protein L5]]
*[[Ribosomal protein L16|Ribosomal protein L16]]
*[[Ribosomal protein L6]]
*[[Ribosomal protein L17|Ribosomal protein L17]]
*[[Ribosomal protein L18|Ribosomal protein L18]]
*[[Ribosomal protein L19|Ribosomal protein L19]]
*[[Ribosomal protein L2|Ribosomal protein L2]]
*[[Ribosomal protein L20|Ribosomal protein L20]]
*[[Ribosomal protein L21|Ribosomal protein L21]]
*[[Ribosomal protein L22|Ribosomal protein L22]]
*[[Ribosomal protein L23|Ribosomal protein L23]]
*[[Ribosomal protein L24|Ribosomal protein L24]]
*[[Ribosomal protein L25|Ribosomal protein L25]]
*[[Ribosomal protein L27|Ribosomal protein L27]]
*[[Ribosomal protein L28|Ribosomal protein L28]]
*[[Ribosomal protein L29|Ribosomal protein L29]]
*[[Ribosomal protein L3|Ribosomal protein L3]]
*[[Ribosomal protein L30|Ribosomal protein L30]]
*[[Ribosomal protein L32|Ribosomal protein L32]]
*[[Ribosomal protein L33|Ribosomal protein L33]]
*[[Ribosomal protein L34|Ribosomal protein L34]]
*[[Ribosomal protein L35|Ribosomal protein L35]]
*[[Ribosomal protein L36|Ribosomal protein L36]]
*[[Ribosomal protein L4|Ribosomal protein L4]]
*[[Ribosomal protein L5|Ribosomal protein L5]]
*[[Ribosomal protein L6|Ribosomal protein L6]]
*[[Ribosomal protein L9|Ribosomal protein L9]]


==Reference==
==Reference==
<ref group="xtra">PMID:20876128</ref><references group="xtra"/>
<ref group="xtra">PMID:020876128</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Cate, J H.D.]]
[[Category: Cate, J H.D.]]
Line 45: Line 57:
[[Category: Protein biosynthesis]]
[[Category: Protein biosynthesis]]
[[Category: Ribosomal subunit]]
[[Category: Ribosomal subunit]]
[[Category: Ribosome]]
[[Category: Ribosome-antibiotic complex]]
[[Category: Ribosome]]
[[Category: Ribosome]]
[[Category: Rna]]
[[Category: Rna]]
[[Category: Transfer]]
[[Category: Transfer]]
[[Category: Trna]]
[[Category: Trna]]

Revision as of 13:42, 25 July 2012

File:3ofc.png

Template:STRUCTURE 3ofc

Crystal structure of the E. coli ribosome bound to chloramphenicol. This file contains the 50S subunit of the first 70S ribosome with chloramphenicol bound.

Template:ABSTRACT PUBMED 20876128

About this Structure

3ofc is a 30 chain structure of Ribosomal protein L11, Ribosomal protein L13, Ribosomal protein L15, Ribosomal protein L16, Ribosomal protein L17, Ribosomal protein L18, Ribosomal protein L19, Ribosomal protein L2, Ribosomal protein L20, Ribosomal protein L21, Ribosomal protein L22, Ribosomal protein L23, Ribosomal protein L24, Ribosomal protein L25, Ribosomal protein L27, Ribosomal protein L28, Ribosomal protein L29, Ribosomal protein L3, Ribosomal protein L30, Ribosomal protein L32, Ribosomal protein L33, Ribosomal protein L34, Ribosomal protein L35, Ribosomal protein L36, Ribosomal protein L4, Ribosomal protein L5, Ribosomal protein L6 and Ribosomal protein L9 with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  1. Dunkle JA, Xiong L, Mankin AS, Cate JH. Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17152-7. Epub 2010 Sep 27. PMID:20876128 doi:10.1073/pnas.1007988107

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