1cdw: Difference between revisions

Revision as of 20:51, 25 July 2012

Structural annotation:
Resources:	CATH : 1Cdwa02, 1Cdwa01 InterPro : Ipr012295, Ipr012294, Ipr000814 Pfam : PF00352 SCOP : d1cdwa1, d1cdwa2 UniProt : P20226

Functional annotation:
Cellular component:	nucleus transcription factor TFIID complex
Biological process:	transcription initiation from RNA polymerase II promoter transcription cell death transcription from RNA polymerase II promoter regulation of transcription, DNA-dependent
Molecular function:	general RNA polymerase II transcription factor activity binding DNA binding protein binding RNA polymerase II transcription factor activity

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

1cdw is a 3 chain structure of TATA-Binding Protein with sequence from Homo sapiens. The July 2005 RCSB PDB Molecule of the Month feature on TATA-Binding Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2005_7. Full crystallographic information is available from OCA.

Nikolov DB, Chen H, Halay ED, Hoffman A, Roeder RG, Burley SK. Crystal structure of a human TATA box-binding protein/TATA element complex. Proc Natl Acad Sci U S A. 1996 May 14;93(10):4862-7. PMID:8643494
Cokol M, Nair R, Rost B. Finding nuclear localization signals. EMBO Rep. 2000 Nov;1(5):411-5. PMID:11258480 doi:10.1093/embo-reports/kvd092
Hicks JM, Hsu VL. The extended left-handed helix: a simple nucleic acid-binding motif. Proteins. 2004 May 1;55(2):330-8. PMID:15048824 doi:10.1002/prot.10630

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 {{STRUCTURE_1cdw|  PDB=1cdw  |  SCENE=  }}
 ===HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA===
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 ==See Also==
-*[[TATA-Binding Protein]]
+*[[TATA-Binding Protein|TATA-Binding Protein]]
 ==Reference==
-<ref group="xtra">PMID:8643494</ref><references group="xtra"/>
+<ref group="xtra">PMID:008643494</ref><ref group="xtra">PMID:011258480</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
 [[Category: RCSB PDB Molecule of the Month]]
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 [[Category: Dna binding]]
 [[Category: Transcription initiation]]
-[[Category: Transcription/dna complex]]
+[[Category: Transcription-dna complex]]