3eig: Difference between revisions

Revision as of 14:41, 27 July 2012

3eig is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Volpato JP, Yachnin BJ, Blanchet J, Guerrero V, Poulin L, Fossati E, Berghuis AM, Pelletier JN. Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance. J Biol Chem. 2009 Jul 24;284(30):20079-89. Epub 2009 May 28. PMID:19478082 doi:10.1074/jbc.M109.018010

@@ Line 1: / Line 1: @@
 [[Image:3eig.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3eig", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3eig|  PDB=3eig  |  SCENE=  }}
 ===Crystal structure of a methotrexate-resistant mutant of human dihydrofolate reductase===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_19478082}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 19478082 is the PubMed ID number.
--->
 {{ABSTRACT_PUBMED_19478082}}
@@ Line 22: / Line 11: @@
 ==See Also==
-*[[Dihydrofolate reductase]]
+*[[Dihydrofolate reductase|Dihydrofolate reductase]]
 ==Reference==
-<ref group="xtra">PMID:19478082</ref><references group="xtra"/>
+<ref group="xtra">PMID:019478082</ref><references group="xtra"/>
 [[Category: Dihydrofolate reductase]]
 [[Category: Homo sapiens]]