3iu3: Difference between revisions

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[[Image:3iu3.png|left|200px]]
[[Image:3iu3.png|left|200px]]


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{{STRUCTURE_3iu3|  PDB=3iu3  |  SCENE=  }}  
{{STRUCTURE_3iu3|  PDB=3iu3  |  SCENE=  }}  


===Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain===
===Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain===


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{{ABSTRACT_PUBMED_20032294}}
{{ABSTRACT_PUBMED_20032294}}


==About this Structure==
==About this Structure==
[[3iu3]] is a 9 chain structure of [[Monoclonal Antibody]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IU3 OCA].  
[[3iu3]] is a 9 chain structure of [[Antibody]] and [[Interleukin receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IU3 OCA].  


==See Also==
==See Also==
*[[Monoclonal Antibody]]
*[[Antibody|Antibody]]
*[[Interleukin receptor|Interleukin receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:20032294</ref><references group="xtra"/>
<ref group="xtra">PMID:020032294</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ding, J.]]
[[Category: Ding, J.]]
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[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Polymorphism]]
[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Simulect]]
[[Category: Simulect]]

Revision as of 14:41, 27 July 2012

File:3iu3.png

Template:STRUCTURE 3iu3

Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain

Template:ABSTRACT PUBMED 20032294

About this Structure

3iu3 is a 9 chain structure of Antibody and Interleukin receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Du J, Yang H, Zhang D, Wang J, Guo H, Peng B, Guo Y, Ding J. Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab. J Immunol. 2010 Feb 1;184(3):1361-8. Epub 2009 Dec 23. PMID:20032294 doi:10.4049/jimmunol.0903178

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