2fzi: Difference between revisions

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Revision as of 01:31, 27 December 2010

File:2fzi.png

Template:STRUCTURE 2fzi

New Insights into DHFR Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives

Template:ABSTRACT PUBMED 17019704

About this Structure

2fzi is a 1 chain structure of Dihydrofolate reductase with sequence from Pneumocystis carinii. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cody V, Pace J, Chisum K, Rosowsky A. New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions. Proteins. 2006 Dec 1;65(4):959-69. PMID:17019704 doi:10.1002/prot.21131

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