2fzi: Difference between revisions

Revision as of 01:05, 27 July 2012

2fzi is a 1 chain structure of Dihydrofolate reductase with sequence from Pneumocystis carinii. Full crystallographic information is available from OCA.

Cody V, Pace J, Chisum K, Rosowsky A. New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions. Proteins. 2006 Dec 1;65(4):959-69. PMID:17019704 doi:10.1002/prot.21131

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 [[Image:2fzi.png|left|200px]]
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 ===New Insights into DHFR Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives===
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 ==See Also==
-*[[Dihydrofolate reductase]]
+*[[Dihydrofolate reductase|Dihydrofolate reductase]]
 ==Reference==
-<ref group="xtra">PMID:17019704</ref><references group="xtra"/>
+<ref group="xtra">PMID:017019704</ref><references group="xtra"/>
 [[Category: Dihydrofolate reductase]]
 [[Category: Pneumocystis carinii]]