1rx5: Difference between revisions

Revision as of 08:13, 27 July 2012

1rx5 is a 1 chain structure of Dihydrofolate reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Sawaya MR, Kraut J. Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry. 1997 Jan 21;36(3):586-603. PMID:9012674 doi:https://dx.doi.org/10.1021/bi962337c
Hu Z, Bowen D, Southerland WM, del Sol A, Pan Y, Nussinov R, Ma B. Ligand binding and circular permutation modify residue interaction network in DHFR. PLoS Comput Biol. 2007 Jun;3(6):e117. Epub 2007 May 11. PMID:17571919 doi:10.1371/journal.pcbi.0030117

@@ Line 1: / Line 1: @@
 [[Image:1rx5.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_1rx5", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_1rx5|  PDB=1rx5  |  SCENE=  }}
 ===DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_9012674}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 9012674 is the PubMed ID number.
--->
 {{ABSTRACT_PUBMED_9012674}}
@@ Line 22: / Line 11: @@
 ==See Also==
-*[[Dihydrofolate reductase]]
+*[[Dihydrofolate reductase|Dihydrofolate reductase]]
 ==Reference==
-<ref group="xtra">PMID:9012674</ref><references group="xtra"/>
+<ref group="xtra">PMID:009012674</ref><ref group="xtra">PMID:017571919</ref><references group="xtra"/>
 [[Category: Dihydrofolate reductase]]
 [[Category: Escherichia coli]]