2fme: Difference between revisions
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[[Image:2fme.png|left|200px]] | [[Image:2fme.png|left|200px]] | ||
{{STRUCTURE_2fme| PDB=2fme | SCENE= }} | {{STRUCTURE_2fme| PDB=2fme | SCENE= }} | ||
===Crystal structure of the mitotic kinesin eg5 (ksp) in complex with mg-adp and (r)-4-(3-hydroxyphenyl)-n,n,7,8-tetramethyl-3,4-dihydroisoquinoline-2(1h)-carboxamide=== | ===Crystal structure of the mitotic kinesin eg5 (ksp) in complex with mg-adp and (r)-4-(3-hydroxyphenyl)-n,n,7,8-tetramethyl-3,4-dihydroisoquinoline-2(1h)-carboxamide=== | ||
{{ABSTRACT_PUBMED_16458511}} | {{ABSTRACT_PUBMED_16458511}} | ||
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==See Also== | ==See Also== | ||
*[[Kinesin]] | *[[Kinesin|Kinesin]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:016458511</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Sheriff, S.]] | [[Category: Sheriff, S.]] | ||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Eg5 ksp mg-adp complex inhibitor]] | [[Category: Eg5 ksp mg-adp complex inhibitor]] | ||
Revision as of 14:49, 25 July 2012
Crystal structure of the mitotic kinesin eg5 (ksp) in complex with mg-adp and (r)-4-(3-hydroxyphenyl)-n,n,7,8-tetramethyl-3,4-dihydroisoquinoline-2(1h)-carboxamide
Template:ABSTRACT PUBMED 16458511
About this Structure
2fme is a 2 chain structure of Kinesin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Tarby CM, Kaltenbach RF 3rd, Huynh T, Pudzianowski A, Shen H, Ortega-Nanos M, Sheriff S, Newitt JA, McDonnell PA, Burford N, Fairchild CR, Vaccaro W, Chen Z, Borzilleri RM, Naglich J, Lombardo LJ, Gottardis M, Trainor GL, Roussell DL. Inhibitors of human mitotic kinesin Eg5: characterization of the 4-phenyl-tetrahydroisoquinoline lead series. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2095-100. Epub 2006 Feb 3. PMID:16458511 doi:10.1016/j.bmcl.2006.01.056
